A couple of weeks back, Bruce and I tested out how well Xenos Rampant works as a skirmish game, using a ship Bruce built and some old 25mm ST:TOS figures that I had. It took us two tries to tweak things, but the result was a surprisingly good sci-fi pulp game.
In the end, it came down to Kirk and Spock duking it out with the Romulan captain and her last security team, which was pretty spot on for the effect we wanted. At 25 points, the game played pretty fast--like 30 minutes maybe? I was surprised how a rule systems not meant for skirmish worked well enough to give dramatic games with tough decisions.